Malvern-Based Medical Device Company Raises Millions for Heart Surgery Technology


A medical device company from Malvern has raised $2.5 million for a groundbreaking heart surgery technology. Excision Inc. aims to use the ‘leaflet modification technology’ to manage a heart condition called ‘aortic stenosis,’ writes John George for the Philadelphia Business Journal.   

Aortic stenosis is when the arteries narrow and the valve becomes stiff, which impacts the blood flow to the heart. A special procedure called TAVR or Transcatheter Aortic Valve Replacement, replaces the thick valve to restore the blood flow. The medical leaflet excision system used in TAVR procedures allows surgeons to excise the leaflets or “flaps” that open and close to let blood flow into the aorta from the left ventricle. 

This leaflet modification technology will be used in re-do TAVR surgeries where a second aortic valve is implanted to replace the old one. It will also help to manage the patient’s blood flow during the procedure.  

The company, founded in 2020, believes that these re-do TAVR procedures are part of an ever-increasing demand for replacement valves. It said that health officials estimates that nearly 2 million Americans will have a bioprosthetic valve implanted to replace their old ones by 2032.  

Read more about this cutting-edge heart surgery technology in the Philadelphia Business Journal.

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